71st ASMS Conference
Mass Spectrometry and Allied Topics
June 4 – 8, 2023 | Houston, USA
At this year's ASMS, MSAID will showcase major feature updates to CHIMERYS, the intelligent search algorithm for proteomics. Don't miss the new capabilities!
Connect with us in Houston
Visit us at booth #707
We are thrilled to announce that we will be participating in the 71st ASMS Conference on Mass Spectrometry this June in Houston. We can't wait to welcome you to our booth #707 located straight across from the main entrance.
At our booth, we would be delighted to discuss the power of CHIMERYS 2.0, our latest proteomics software packed with advanced features and improvements that will help take your research to the next level.
We look forward to seeing you in Houston! #ASMS2023
Our Poster Presentations at ASMS 2023
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Poster ThP 041: Analyzing data-independent acquisition (DIA) data one experimental spectrum at a time.
Topic Area: Data-Independent Acquisition II
Date and Time: Thursday, June 8, 2023, 10:30 am - 2:30 pmDIA spectra are inherently chimeric due to the co-isolation of multiple peptide precursors. We have previously shown that DDA spectra can also be substantially chimeric and introduced a method to deconvolute them one spectrum at a time, distributing the intensities of shared fragment ions to precursors instead of discarding them. Here, we show that this approach generalizes to any chimeric MS2 spectrum, harmonizing the analysis of DDA and DIA data. -
Poster MP581: Digging deeper into phosphoproteomes through AI-driven deconvolution of chimeric spectra.
Topic Area: Phosphopeptides and phosphoprotein
Date and Time: Monday, June 5, 2023, 10:30 am - 2:30 pmThe mass spectrometry-based analysis of biochemically enriched phoshopeptides requires accurately localizing the post translational modification within the peptide. Here, we extend the capabilities of our deep-learning framework to accurately predict physicochemical properties of phosphorylated peptides and demonstrate the usefulness of these predictions for improving the identification, correct localization, and accurate quantification of protein phosphorylation from bottom-up proteomic datasets.
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Poster WP375: Fully automated and spectrum-centric processing of parallel reaction monitoring (PRM) data
Topic Area: Informatics: General, SRM, and DIA
Date and Time: Wednesday, June 7, 2023, 10:30 am - 2:30 pmTargeted mass spectrometry assays are the gold standard for the quantification of low abundant peptides and biomarkers. Here, we showcase a fully automatic algorithm that identifies and quantifies peptides in PRM data, thus removing a major obstacle when developing or applying targeted assays. -
Poster TP380: CHIMERYS server: deploying the power of the cloud in your basement
Topic Area: Informatics: Workflow and Data Management
Date and Time: Tuesday, June 6, 2023, 10:30 am - 2:30 pm
The CHIMERYS search engine is deployed as a subscription-based cloud service on Amazon Web Services (AWS) with a client interface for Proteome Discoverer software (PD). Here, we describe the adaptation of the CHIMERYS cloud service to an on-premise solution for single servers and HPC environments, addressing user requirements while minimizing redundancy and keeping the best of both worlds wherever possible, as well as a command line interface (CLI) for CHIMERYS.